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Mr. Mackey Buys Pants is an April Fools South Park fangame posing as a fangame called "Trapper Keeper Revolutions" (based on a South Park episode from season 4 called Trapper Keeper) by "Beamer", which has a screamer at the end.
The game opens with a Beamer Games logo, announced in a deliberately silly voice, followed by a menu with "MR MACKEY BUYS PANTS" being repeated chanted in an equally moronic sounding voice. The player controls the South Park character, Mr. Mackey, who wanders around in a world of trousers.