Madoka.exe
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madoka.exe, mostly known as the Ghost virus or the Sadako virus in Japan, is a Japanese joke program, which is a variant of the Win32/FlaGhost Malware.
When the user runs the program, a picture of a Japanese woman in full-screen is displayed briefly, before disappearing. Some Chinese text is then displayed in the upper-left corner of the screen. However, a ghost version of the woman image will suddenly appear along with a scream sound effect. When the screamer ends, it will immediately switch back to the woman picture.
A similar version of this application exists, called hikaru.exe. Both programs seem to do the same things, but they have a different screamer picture.