Creatures Pre-Roll

Creatures Pre-Roll is a anti-smoking ad made by The Real Cost on July 15, 2015, the commercial does contain a screamer

The ad starts with a dark setting, and an animated cigarette box shaking. When the video reaches 4 seconds, a large monstrous red spider-like creature gets out from the box of cigarettes, screaming and repeatedly hitting the screen. The creature goes away, and some text appears saying: "If cigarettes looked as dangerous as they are, you'd #runlikehell".

Link
NOTE : The following video contains a screamer.
 * youtube.com/watch?v=TnHydQ94Z_Y